Hello Mrtrix Team,
for a study I would like to compare DWI data of two groups, one is doing sport and the other not and only serve as comparison. I would like to analyse the WM integrity. I found on your webpage different topics and terms, such as AFD, FC, and FDC. However I have still some questions:
- What would you suggest to do for such project? Doing the fixel based analysis as described in: http://mrtrix.readthedocs.io/en/latest/fixel_based_analysis/mt_fibre_density_cross-section.html?highlight=afd
or is it enough to calculate and compare AFD maps via fod2fixel and fixel2voxel, or is there another approach implemented in MRtriX?
2.What are exactly the differences between the metrics AFD and FC, FC and FDC?
- The fixel based tutorial includes also tractography (19-22), are these steps necessary in case of a WM integrity comparison?
Thank you for your support!!!