I would like to create an atlas of TWIs. I also used the population_template script on FODs data and it works well.
However I have two questions on the pipeline:
population_template can works with FA images, FODs,TWIs. Which one is the better to create an atlas? Is there any documentation on the different pipelines?
To obtain the TWI in my template space, I think I have 3 possibilities: a) estimate the tractograms directly on the FOD in the template space then estimate the TWI, b) estimate the tractograms and the TWIs in the patient space then apply the transform to the template space, c) estimate the tractograms on the patient space then apply the transform to the template space and estimate the TWI.
Which one is the better or suggested?
I saw this recommendations for the HCP in previous post on the forum:
“The general recommendation would be to normalize the streamlines to template space, and then generate the ‘number of connections’ image in template space. This is preferable to warping a density image, as the orientation dependence of density modulation based on expansion / contraction in the warp field will be performed correctly.”
Thanks by advance