I am new to using MRtrix and I was hoping to get some feedback about the results I have. I followed the instructions to perform fixel-based analysis using single tissue CSD. The data I’m using is b=3000 s/mm2 with 60 directions.
Below is a figure of the fixels that show p<0.05 when looking for group differences between the two groups I have. It looks like the forceps major but also looks like it could be in the ventricles. The groups have difference in ventricle size so this is a bit unsettling. With the high b value there should be little signal from the CSF, so I’m not sure if the differences in the ventricles would be causing this? Would using multiple tissue CSD and fitting models to only WM and CSF help in this case? Any thoughts would be greatly appreciated. Thank you!!