Hi Brady,
Thanks for your interest! I’ve sadly not found the time to make a public implementation of SS3T-CSD available yet (note as well the subtle name change we’ve been trying to push in the mean time, ever since I came up with the potentially confusing old 2S3T-CSD name). But, as with many things, it’s on the TODO list (quite high up there in terms of priorities though). The alternate approach we’ve been advising to some people in some specific scenarios for a little while now, is to do a “2-tissue” CSD, using only WM and CSF responses together with the MSMT-CSD algorithm (dwi2fod msmt_csd). You’ll benefit of some free-water-and-a-little-bit-more elimination, as well as from the so-called “hard constraint” that is implemented in the msmt_csd algorithm (versus the so-called “soft constraint” in the basic csd algorithm). See this post for some advice that we’ve been referring some people to.
Out of curiosity: what kind of data are you sitting on? Does it have a high b-value (let’s say 2500s/mm^2 or larger) and decent angular resolution (let’s say 60 directions or thereabouts, or more of course)? Depending on your scenario, I could try and help you out, if it makes sense of course. I’ll be at ISMRM from the end of next week by the way, if you want to get in touch.
Cheers,
Thijs