# 5tt\_nocoreg.mif missing frontal cortex

**URL:** <https://community.mrtrix.org/t/5tt-nocoreg-mif-missing-frontal-cortex/7305>\
**Category:** Uncategorized\
**Tags:** tractography\
**Created:** [January 18, 2024, 5:13pm UTC](https://community.mrtrix.org/t/5tt-nocoreg-mif-missing-frontal-cortex/7305 "2024-01-18T17:13:32Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![adsouza](https://community.mrtrix.org/user_avatar/community.mrtrix.org/adsouza/32/4571_2.png) [@adsouza](https://community.mrtrix.org/u/adsouza)\
**Post date:** [February 2, 2024, 1:04am UTC](https://community.mrtrix.org/t/5tt-nocoreg-mif-missing-frontal-cortex/7305/2 "2024-02-02T01:04:39Z")

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Hi Holly,  
Check out the following post.

> [@Challenges with Seed Generation using '5ttgen fsl' for Anatomically Constrained Tractography](https://community.mrtrix.org/t/challenges-with-seed-generation-using-5ttgen-fsl-for-anatomically-constrained-tractography/7216/2):
>
> Hi Kenbridge6, Running bias field correction on the anatomical image before 5ttgen fsl may help produce segmentations that are more accurate… I cannot guarantee that it will improve the segmentation quality, but might be worth a go slight_smile Cheers, Arkiev

Does it happen systematically, or is this occurrence only in a single subject? Screenshots of the input T1 into `5ttgen` might be helpful in identifying a solution 🙂

Hope this helps!

Cheers,  
Arkiev

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