# Poor registration with mrregister compared with ANTs

**URL:** https://community.mrtrix.org/t/poor-registration-with-mrregister-compared-with-ants/1233
**Category:** Uncategorized
**Tags:** registration
**Created:** [October 12, 2017, 2:54pm UTC](https://community.mrtrix.org/t/poor-registration-with-mrregister-compared-with-ants/1233 "2017-10-12T14:54:30Z")
**Posts on this page:** 1
**Showing post:** 4

<div class="post-metadata">

### Author: ![maxpietsch](https://community.mrtrix.org/user_avatar/community.mrtrix.org/maxpietsch/32/25_2.png) [@maxpietsch](https://community.mrtrix.org/u/maxpietsch)
#### Post date: [October 16, 2017, 11:11am UTC](https://community.mrtrix.org/t/poor-registration-with-mrregister-compared-with-ants/1233/4 "2017-10-16T11:11:36Z")

</div>

I’d second that, the mean squared metric is likely not suitable for cross-modality registration. I’ve managed to linearly (affine) register across modalities using combinations of manually fine-tuned contrasts to give similar contrast and intensity ranges but the results of nonlinear registration are unusable more often than not.

@EricMoulton_ICM If you want, you can send me a link with a subject’s FOD, tensor (`dwi2tensor`) and b0 (`dwiextract`) image and I can give it a try.

> [@ThijsDhollander](#):
>
> You’ve got any (near) future plans for such features?

No near future plan but we definitely should… If anyone wants to take this on, I’d start in the `mrreg` branch.

Cheers,  
Max

---

_[View the full topic](https://community.mrtrix.org/t/poor-registration-with-mrregister-compared-with-ants/1233)._