Dear All,
I am working on DWI images and want to understand whether the selection of the files for denoising will impact the quality of the final results. I have data of 80 volumes of DWIs (25 volumes of b1000, 24 volumes of b2000, 24 volumes of b3000, and 7 volumes of b0) in PA direction. In addition, I have 2 volumes of b0 in AP and 2 volumes of b0 in PA direction of the same subject in the same run.
Now, I want to understand what should be the ideal pipeline of preprocessing. Following are my approaches:
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Denoise AP b0 (2 volumes), PA b0 (2 volumes), and DWI (80 volumes) separately.
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Denoise AP- PA b0 pair (4 volumes) after concatenation and separately denoise DWI (80 volumes).
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Denoise all the available volumes i.e. AP- PA-DWI (84 volumes) altogether.
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Denoise AP b0 (2 volumes) and PA-DWI (82 volumes) separately.
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Denoise only DWI (80 volumes), and process AP-PA b0 pairs (4 volumes) directly into fsl topup without performing denoising.
If anybody has tried any of these approaches and achieved significant results, then let me know.
@Mrtrix_developers if you have come across any such query earlier in the past then connect me to that discussion. Also, give me your valuable inputs on each of the approaches, what can be the possible disadvantage and advantage of using each of the approaches.
Thank you in advance for giving your time.
Muskan Khetan