Tckgen input options

I would like to have some further clarifications on the following options for streamline seeding, since from the documentation they are not totally clear:
-seed_image image (multiple uses permitted) seed streamlines entirely at random within a mask image → how should this mask be created? According to which criteria?

-seed_sphere spec (multiple uses permitted) spherical seed as four comma-separated values (XYZ position and radius) → how should this sphere be created? According to which criteria?

thanks in advance