Tractography in the presence of Edema

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Hi Parand,

This post might help explain the behaviour of streamlines within structures labeled as PATH in the 5TT image.

My understanding is that, unlike the other tissue types, PATH does not impose anatomical constraints on streamlines. More specifically:

  • Unlike CSF, streamlines are allowed to pass through PATH regions rather than being stopped.
  • Unlike SGM, streamlines do not necessarily terminate in PATH tissue - they can continue propagating through it.
  • If FODs are unreliable or missing within PATH regions, streamlines may behave erratically or follow random trajectories.

Hope this helps! :slightly_smiling_face:
Arkiev