Hi all! I have a question related to DWI data registration and FOD-based information that we want to incorporate into our subsequent analysis steps. We are working with a data set of patients and we have two sessions for each patient with DTI measures - at two different time-points following a str…

Hi Ivana, I’d suggest you use a single (set of) response function(s) for your analysis. Think of it as a common basis that allows you to directly compare the FOD coefficients. If you have reason to believe that the stroke adversely affects single fibre voxels (see output of dwi2response -voxels) in…

Hi fellow mrtrixers, Just a follow-up clarification on this point. We have a similar longitudinal design with multi-shell dwi data collected at two timepoints (and soon adding a third timepoint). After reading the documentation further and some of the posts on the forum, I understand that estimatin…

Hi Maria, Yes, a single set of response functions is usually what you want. You don’t have to use all data to calculate these. All of the points in my previous response hold true for more than two time points. Personally, I’d use all time points and subjects but you can use a representative subset …

Thank you very much for the detailed explanation! :slight_smile:

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DWI Data registration and FOD comparisons

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