Fiber tracts for corpus callosum

Greetings. I want to fiber tractography using mrtrix. I am specifically interested in visualizing corpus callosum tracts. I want to compare the tracts for visualization (ground truth tracts for b = 2000 shell data from the hcp dataset with my predicted b = 2000 tracts from a reconstructed data).

Basically, i want to compare tracts like the one shown above.. So far, I have obtained the white matter fodf map and generated white matter tracts like below (shown in coronal view)…

what are the next steps from here ? How to draw proper ROIs and extract the cc tracts as required. Can someone explain in little detail ?

Regards

Hi Hirak,

You might consider using tractseg ( GitHub - MIC-DKFZ/TractSeg: Automatic White Matter Bundle Segmentation ), See for example, smeisler (Steven Meisler) · GitHub smeisler Meisler_Reading_FBA and how to use “own” Wmfod’s in fba/bash_scripts/8b_tractseg.sh.

Cheers

William

Hi Hirak,

There are many atlases available in MNI space, and many will include parts of the corpus callosum (I know the Harvard atlas that comes with FSL has it). I would warp these ROIs into T1 space nonlinearly, then affine into DTI. You can use tckedit to extract streamlines based on whether they pass through the ROIs, which should give you your desired streamlines.

Good luck!

Rishi