I have a question about tckedit command. Before, I used another software (DSI Studio) to dissect white matter fibers virtually. I am not a fan of ROI-based tractography, because over the years I found it to produce bundles that are smaller in volume. However, I do virtual dissection for all my patients’ data despite it is a time-consuming process but the results are much better in my opinion. Usually, in the beginning, I run an analysis with 10K streamlines of the white matter (to save memory) and do a virtual dissection to those streamlines to bring a certain tract (e.g., SLF2). This tract’s streamlines are later converted into masks. After that, I will run tractography for 3 million or more streamlines for the white matter and use that mask to filter “streamlines” running “totally” within that mask. In other words, the streamlines that exiting the mask will be “eliminated.”
When I tried to apply the same concept with mrtrix tckedit using -mask option, I faced a problem. The mask will not eliminate those tracts that exit the mask, but instead, it will truncate them. Then, I would end with a mask containing the targeted tract (the SLF2) and several other truncated white matter bundles.
Is there a way by using a mask to filter unwanted streamlines by eliminating and not truncating?
Hope to hear your suggestions and recommendations. Thanks.