Dear Experts,
I am keen to perform a fixed based analysis using mouse diffusion data (b value 1500).
Is this feasible and are they any considerations I should be aware of?
Thanks for your help
Peter
Dear Experts,
I am keen to perform a fixed based analysis using mouse diffusion data (b value 1500).
Is this feasible and are they any considerations I should be aware of?
Thanks for your help
Peter
I think so - I certainly can’t see any a priori reason why not.
Yes! But far too many to go into here…
Without any further information, the main ones at this point are:
Make sure you have enough computing power, especially RAM (as documented in the warning at the end of this section of the documentation).
Are your data in vivo or ex vivo? If the latter, I reckon your b-value is far too low to get decent angular contrast… As shown by Tim Dyrby a while back, you need to scale up your ex vivo b-values by a factor of ~4 for comparable contrast to the in vivo case.
There’s no doubt a million other things to take into consideration, but for that you’re better off reading as much of the relevant literature as possible…