Hi all MRtrixers,

after I preprocessed my data using MRtrix3, in some steps FSL respectively (b values 700, 1000 and 2300) I need to calculate kurtosis parameters. I found 2 ways for it - **DESINGER** or **DKE** (Diffusional Kurtosis Estimator). Is there any suggestion/recommendation in using one of theme? Or your personal opinion?

I saw J Varaart, 2013 in references for both dwi2tensor and Designer’s *dki_fit* function on github. Does it mean that I can calculate kurtosis tensor using dwi2tensor and for calculation of metrics I can call just Designer’s *dki_parameters* function?

I found that DESIGNER use some of MRtrix3 functions. That this mean that it is more suitable for parametrs estimation than DKE?

Thanks for all of your advices. I appreciate it.