I am working with pre-term and term born infant diffusion MRI data with HARDI acquisition ( 6 b=0, 30 b=700, 60 b=2800) . I am currently applying different microstructural models to those data (such as DKI, NODDI, FORECAST, MAPL and Multi-Shell Multi-Tissue CSD). As for all the models, default parameters seem to work well, with exception for MSMT-CSD. Indeed 55tgen algortihm seems to take too much time for some subjects without never terminating. Moreover, I have read it is not suitable for neonates due to poor WM/GM contrast.
Here you find attached an example outcome for 5ttgen algorithm applied to one subject. In order there are: csf, wm and gm tissue contribution map.
Instead, this is the 5tt.mif image
and finally, this is the WM fODFs displayed together with the tissue signals contribution map
Are they satisfactory?
I have at disposal 3dT1 and HARDI dMRI data for those infants, not the T2 image. Is there an alternative way with these data to compute MSMT-CSD?