Hello,
Is it possible to perform FBA at the subject level instead of the group level? For instance, if it’s already possible to generate the tissue response functions and the population template using a subset of DWI data, then shouldn’t it also be possible to generate those outputs for a particular protocol and then use those outputs for any future FBA at the subject level that uses the same protocol? Here is what I think the workflow would look like:
- Select a small cohort of healthy DWI data that were acquired using the same protocol.
- Exclusively use the cohort from step 1 to generate tissue response functions, an FOD template, a template mask, and a fixel mask.
- Perform FBA using the outputs mentioned in step 2 on any other DWI data that were acquired using the same protocol.
Does this workflow make sense or is there something I’m not seeing that makes protocol-specific FBA at the subject level not possible?
Thanks,
Mike