Hello, I am new to MRtrix3. Could you please guide me to the processing of DTI
tractography?
I have used Andy’s Brain Book in the past: MRtrix Introduction: Overview of Diffusion Imaging — Andy's Brain Book 1.0 documentation
But it doesn’t discuss group analysis, namely the need to use a common response function. That is discussed in this thread: Group analysis
Regarding group comparisons, my impression is that it is an evolving area and I have seen recommendations to multiply each connectome with the “mu” value output by SIFT2 (which was not explicitly mentioned in the thread above, but is discussed in the threads below):
From reading this paper on the topic, I think the connectome comparisons are still valid even if you don’t multiply each connectome with its mu proportionality coefficient, but the interpretation is different; without scaling by mu, the connectomes would represent relative proportions of white matter fibers within the subject, and scaling by mu is necessary to get them to represent an absolute measure of bundle capacity.
The B.A.T.M.A.N. tutorial is a great resource to learn mrtrix!